Tech Notes

Q. What is the hierarchical clustering algorithm used in GeneSpring?

A. GeneSpring uses the 'centroid' clustering method. In this method, the distance between two clusters is the distance between the averages of the data points under one branch and the averages of the data points under another. This method is sometimes referred to as the "average-linkage" method, although it is not the same as the "true average-linkage" method, which takes the average of all pair wise distances under a tree branch.